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Study Finds Aspirin Does Not Boost Miscarriage Risk NewsMax.com Wires NEW YORK -- A new study has found no increased risk of miscarriage with aspirin use. But more research is needed, the study's lead author told Reuters Health, to establish that aspirin is indeed safe for pregnant women. "The findings of this study indicate that taking aspirin may not be risky, but women should really talk with their doctor before taking aspirin or anything else if they are pregnant," Sarah A. Keim of the National Institute of Child Health and Human Development in Bethesda, Maryland, said in an interview. Recent studies have linked nonsteroidal anti-inflammatory drugs (NSAIDs), which include aspirin and many other painkillers, to a greater risk of miscarriage, Keim and her colleague Mark A. Klebanoff note in their report in the journal Epidemiology. While aspirin is no longer widely used as a painkiller, they add, some physicians recommend it to women who are trying to become pregnant and have had several miscarriages, based on the possibility that the drug could treat underlying inflammation or clotting abnormalities that may be responsible for pregnancy loss. "But that's controversial," Keim said. To further look at whether aspirin might have any relationship to miscarriage, the researchers analyzed data from a study of 54,000 pregnant women conducted between 1959 and 1965, when aspirin use in pregnancy was more common and other NSAIDs were not available. They compared aspirin use among 542 women who miscarried and 2,587 who delivered healthy babies. Twenty-nine percent of the women who miscarried and 34 percent of those who did not reported using aspirin while pregnant, Keim and Klebanoff found. They found no link between taking aspirin during months two and three of pregnancy and miscarriage, while taking it during the fourth and fifth month of pregnancy was actually linked to a lower miscarriage risk. "Future research on the effect of aspirin use before and at different times during pregnancy is needed to assure that its deliberate use in assisted reproductive technologies is not deleterious to pregnancy and to assess ongoing risk from incidental use unrelated to pregnancy," the researchers conclude. Story Continues Below
"Even though aspirin might be an old drug and many people don't take it anymore, it's readily available and might be worth taking a closer look at, especially with recent studies that have pointed to some of the newer NSAIDs having unintended side effects," Keim added. SOURCE: Epidemiology, July 2006.
Copyright Reuters 2006. All rights reserved. Republication or redistribution of Reuters content, including by caching, framing or similar means, is expressly prohibited without the prior written consent of Reuters. Editor's note: Read more on this subject in related Hot Topics:
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