Your weight at midlife may be a large factor in whether you wind up with Alzheimer's disease as a senior citizen, according to a new study from Sweden.
People who were considered obese at midlife were more than twice as likely as normal weight individuals to have some form of dementia 20 years later, according to a report in the current issue of The Archives of Neurology.
Dr. Miia Kivipelto, and colleagues from the Karolinska Institute in Stockholm, studied nearly 1,500 people for more than 20 years.
Individuals who were obese at midlife were nearly 2 1/2 times more likely to develop Alzheimer's disease or other dementias when they were in their late 60s and 70s. High blood pressure and total cholesterol levels at midlife also doubled the risk.
When together, the risk factors had an additive effect. If a person had all three risk factors at midlife, for example, the risk of dementia or Alzheimer's disease increases sixfold.